Luckily there's a lot of information online, including a demo file: ftp://ftp.dante.de/tex-archive/biblio/bibtex/contrib/achemso/
Anyway, here's a simple file that can act as a template. Have a look at the demo file at ftp.dante.de for a much more exhaustive example, including how to use schemes and insert references.
You can figure out the journal abbreviations from their URLs. Otherwise, page 4 in this pdf has a list: http://www.tug.org/texlive/Contents/live/texmf-dist/doc/latex/achemso/achemso.pdf
Anyway:
\documentclass[journal=inoraj, layout=twocolumn]{achemso}
\usepackage[latin1]{inputenc}
\usepackage[english]{babel}
\usepackage{amsmath}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{graphicx}
\author{Vera Hill}
\affiliation{Department of Chemistry, This University, This Country}
\email{my@email}
\author{I. Lindqvist}
\affiliation{Department of Chemistry, Another University, That Country}
\title{A quick, non-exhaustive tex template}
\begin{document}
\maketitle
%\begin{tocentry} %graphical TOC
%\includegraphics{example.eps}
%TOC text goes here
%\end{tocentry}
\begin{abstract}
The ACS should provide a simple template. They don't, so I do.
\end{abstract}
\section{Introduction}
\section{Results and Discussion}
%\begin{figure}
% \includegraphics{graphic}
% \caption{A figure}
% \label{fig:example}
%\end{figure}
\subsection{References}
\section{Experimental}
\begin{acknowledgement}
VH thanks the internet. IL thanks the electron.
\end{acknowledgement}
\begin{suppinfo}
See supporting information for additional experimental details.
\end{suppinfo}
\end{document}
Example:
